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Chantix Zyban

Chantix (varenicline) and Zyban are the two popular prescription medicines which help the adults to get rid of their smoking habit. Although they work for the same cause but the two medicines differ from each other in many ways. Let us understand the principle differences between the two;

Varenicline or Chantix is a smoking cessation pill which has been designed to reduce nicotine craving and withdrawal effects in smoking men. It works by blocking the receptors in the brain that are linked to an addiction of nicotine. On the other hand Zyban, is mainly an antidepressant which was later approved as smoking cessation medicine by FDA in the year 1997. Its smoking cessation mechanism is yet to be discovered by the scientists. The comparative studies show that Chantix is far more effective than Zyban even with fewer dosages.

As per the three studies published in the July 5 Journal of the American Medical Association, Chantix performs better than placebos in the short term as well as long term treatment for smoking addiction, and is found more effective than Zyban medication normally as well as under different circumstances.

The table below shows the key differences between Chantix and Zyban;


# The manufacturer is pfizer

# Varenicline or Chantix is a smoking cessation medicine.

# Chantix was approved by FDA on May 11, 2006

# Varenicline is designed to reduce nicotine craving and withdrawal effects

# It blocks the receptors in the brain that are linked to an addiction to nicotine.

# The active ingredient in Chantix is Varenicline Tartrate

# A 12 week study shows success rate of 44% in smoking cessation

# 1 year study shows 22% abstinance

# Chantix 1 MG twice daily dose is most effective compared to any other smoke cessation medicine.

# Chantix medication is not recommended in combination with any other smoking cessation medicines.

# Manufacturer is GlaxoSmithKline.

# Bupropion or Zyban is an aid to smoking cessation treatment.

# Zyban was approved by FDA on May 14, 1997

# It was designed mainly to treat a condition called major depressive disorder.

# The mechanism which enhances the ability of patients to abstain from smoking is unknown.

# The active ingradient in Zyban is Bupropion Hydrochloride

# A 12 week study shows Success rate 29.5 % in smoking cessation

# 1 year study shows 16% abstinance

# Zyban 150 MG twice daily dose works better than placebo but less effective compared to Chantix.

# Combination treatment of ZYBAN and NTS may be prescribed for smoking cessation.

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